Microflow reaction is important for the miniaturization of chemical devices and systems. From an engineering perspective, excellent characteristics, including narrow residence time distribution, rapid reactant mixing, fast mass and heat transfer, and effective droplet morphology control, of segmented liquid–liquid flow in microspace are summarized in this review based on recent research progress in the areas of microfluidics, flow chemistry, micro total analysis, and microreaction engineering. Via engineering, important roles of segmented liquid–liquid flow, such as improvements in production yield, inline purification of intermediates and products, creative droplet reactors, and preparation of particle materials with various structures, are introduced. The scale-up of micro devices and large-scale production of chemicals through microflow technology are also discussed, showing good prospects in research and industrial application.

中文翻译：

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液-液微流反应工程

微流反应对于化学装置和系统的小型化很重要。从工程学的角度，本综述基于对微空间的最新研究进展，总结了微空间中分段的液-液流的优异特征，包括狭窄的停留时间分布，快速的反应物混合，快速的质量和热传递以及有效的液滴形态控制。微流体，流化学，微量总分析和微量反应工程领域。通过工程方面，介绍了液-液分流的重要作用，例如提高产量，在线纯化中间体和产品，创新的液滴反应器以及制备具有各种结构的颗粒材料。还讨论了微型设备的规模化和通过微流技术的大规模化学生产，在研究和工业应用中显示出良好的前景。