当前位置: X-MOL 学术React. Chem. Eng. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Ozonolysis of quinoline and quinoline derivatives in a Corning low flow reactor
Reaction Chemistry & Engineering ( IF 3.4 ) Pub Date : 2017-07-31 00:00:00 , DOI: 10.1039/c7re00084g
Kyoungmi Lee 1, 2, 3, 4 , Hongkun Lin 1, 2, 3, 4 , Klavs F. Jensen 1, 2, 3, 4
Affiliation  

Efficient ozonolysis of quinoline, electron deficient 8-nitroquinoline, and electron rich 6-methoxyquinoline is conducted in a Corning low flow reactor (Corning LFR) with recycling. The conversions of quinoline and 8-nitroquinoline from single-pass experiments were 75.6 and 52.4%, respectively. Upon successive oxidative work-up in a batch reactor, pyridine-2,3-dicarboxylic acid was obtained in 72.7 and 24.7% yields from the ozonolysis products of quinoline and 8-nitroquinoline, respectively. The recycling increased the overall conversions to 95.2 and 76.9%, respectively. For 6-methoxyquinoline, the conversion from the single-pass experiment, 45.2%, was increased to 73.5% with recycling under a higher liquid flow rate and substrate concentration for ozonolysis. Experimental results, conversions, residence time distribution (RTD), and the overall mass transfer coefficient are included in reactor models to determine the rate constants for ozonolysis. Predictions with the rate constants for quinoline, 8-nitroquinoline, and 6-methoxyquinoline show good agreement with the experimental results for different recycle ratios and concentrations of ozone and substrates.

中文翻译:

在康宁低流量反应器中对喹啉和喹啉衍生物进行臭氧分解

在循环利用的康宁低流量反应器(Corning LFR)中进行喹啉,缺电子的8-硝基喹啉和富电子的6-甲氧基喹啉的高效臭氧分解。单次通过实验得到的喹啉和8-硝基喹啉的转化率分别为75.6%和52.4%。在间歇反应器中进行连续的氧化处理后,分别从喹啉和8-硝基喹啉的臭氧分解产物中分别获得72.7和24.7%的吡啶-2,3-二羧酸。回收利用将总转化率分别提高到95.2%和76.9%。对于6-甲氧基喹啉,单次通过实验的转化率(45.2%)在较高的液体流速和更高的臭氧分解底物浓度下可通过再循环提高到73.5%。实验结果,转换,停留时间分布(RTD),反应器模型中包括总传质系数,以确定臭氧分解的速率常数。喹啉,8-硝基喹啉和6-甲氧基喹啉的速率常数的预测与臭氧和底物的不同再循环比和浓度下的实验结果显示出良好的一致性。
更新日期:2017-10-03
down
wechat
bug