Original citation: J Clin Invest. 2014;124(5):2009–2022. https://doi.org/10.1172/JCI71951

Citation for this expression of concern: J Clin Invest. 2017;127(10):3913. https://doi.org/10.1172/JCI97015

The Editors recently became aware that some of the flow cytometry plots in this article were duplicated and used to represent different samples. Specifically, in Figure 5C, the flow cytometry plots of IFN-γ– and IL-17–stained cells from IgG1- and CXCL10-Ig–treated animals are from the same sample. In addition, in Figure 7A, the spinal cord samples from the PBS- and IgG1-treated animals are the same; the spleen samples from the CXCL11-Ig– and IgG1–treated animals are the same; and the lymph node samples for the PBS- and IgG1-treated animals are the same. The authors were unable to provide the original data for these figures. The Journal subsequently requested an institutional investigation by the Technion – Israel Institute of Technology, which was recently completed. The investigative committee concluded that identical data were presented twice in the publication and that the raw data were not archived for the amount of time required by Technion. The authors have stated that the errors were unintentional.

The Editorial Board is issuing this Expression of Concern to alert readers to the problems identified in Figures 5C and 7A. The Editors have requested that the experiments in question be repeated by the authors and resubmitted to the Journal. We will inform our readers of the outcome after the data have been evaluated.

Footnotes

See the related article at CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis.

原始引文：J Clin Invest。2014; 124（5）：2009-2022。https://doi.org/10.1172/JCI71951

对此表达关注的文献：J Clin Invest。2017; 127（10）：3913。https://doi.org/10.1172/JCI97015

编辑最近发现，本文中的某些流式细胞仪图已被复制并用于代表不同的样品。具体来说，在图5C中，来自IgG1和CXCL10-Ig处理过的动物的IFN-γ和IL-17染色细胞的流式细胞仪图来自同一样品。另外，在图7A中，来自PBS和IgG1处理过的动物的脊髓样品是相同的。用CXCL11-Ig和IgG1处理过的动物的脾脏样品是相同的；PBS和IgG1处理动物的淋巴结样本相同。作者无法提供这些数字的原始数据。该杂志随后要求Technion-以色列理工学院进行机构调查，该调查最近完成。调查委员会得出的结论是，相同的数据在出版物中两次出现，并且原始数据没有在Technion要求的时间内存档。作者指出，这些错误是无意的。

编辑委员会正在发布此关注表达，以提醒读​​者注意图5C和7A中标识的问题。编辑们要求作者重复上述实验，并重新提交到“日刊”。评估数据后，我们将把结果告知读者。

脚注

参见相关文章，了解FOXP3负调节性T细胞的CXCL11依赖性诱导抑制自身免疫性脑脊髓炎。