RNA editing results in the site-specific conversion of adenosine to inosine in mRNAs. Genomics has revealed millions of editing sites in metazoans, but examining the spatial aspects of editing in cells has been challenging. A new method, inosineFISH (inoFISH), provides the ability to detect edited and unedited mRNAs within intact cells.

中文翻译：

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可视化核RNA编辑

RNA编辑导致mRNA中腺苷向肌苷的位点特异性转化。基因组学已经揭示了后生动物中的数百万个编辑位点，但是检查细胞中编辑的空间方面一直是一项挑战。一种新的方法inosineFISH（inoFISH）提供了检测完整细胞内已编辑和未编辑mRNA的功能。