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Hitting malaria where it hurts
Nature Microbiology ( IF 20.5 ) Pub Date : 2017-09-26 00:00:00 , DOI: 10.1038/s41564-017-0036-z Thierry Diagana , Catherine Jones
Nature Microbiology ( IF 20.5 ) Pub Date : 2017-09-26 00:00:00 , DOI: 10.1038/s41564-017-0036-z Thierry Diagana , Catherine Jones
Hitting malaria where it hurts
中文翻译:
在痛苦中击中疟疾
在痛苦中击中疟疾
更新日期:2017-09-26
Nature Microbiology, Published online: 26 September 2017; doi:10.1038/s41564-017-0036-z
The goal of malaria eradication is threatened by drug resistance. Now, two studies characterize Plasmodium falciparum PKG inhibitors and hexahydroquinolines as antimalarial compounds that could block transmission and help mitigate the risk of parasite escape via drug resistance.
中文翻译:
在痛苦中击中疟疾
在痛苦中击中疟疾
《自然微生物学》,在线发布:2017年9月26日; doi:10.1038 / s41564-017-0036-z
消灭疟疾的目标受到耐药性的威胁。现在,两项研究将恶性疟原虫PKG抑制剂和六氢喹啉类药物定性为抗疟疾化合物,可阻止其传播并通过耐药性帮助降低寄生虫逸出的风险。