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Glioblastoma: Stem cells — masters of their fates
Nature Reviews Cancer ( IF 72.5 ) Pub Date : , DOI: 10.1038/nrc.2017.88 Conor A. Bradley
Nature Reviews Cancer ( IF 72.5 ) Pub Date : , DOI: 10.1038/nrc.2017.88 Conor A. Bradley
Glioblastoma: Stem cells — masters of their fates
中文翻译:
胶质母细胞瘤:干细胞-命运的掌握
胶质母细胞瘤:干细胞-命运的掌握
更新日期:2017-09-25
Nature Reviews Cancer, Published online: 25 September 2017; doi:10.1038/nrc.2017.88
Using DNA barcoding, Lan et al. investigated the clonal evolution and dynamics of glioblastoma cells, and propose a model whereby proliferative heterogeneity is derived from stochastic fate decisions made by a homogeneous population of glioblastoma stem cells and their progeny.
中文翻译:
胶质母细胞瘤:干细胞-命运的掌握
胶质母细胞瘤:干细胞-命运的掌握
Nature Reviews Cancer,在线发表:2017年9月25日;doi:10.1038 / nrc.2017.88
Lan等人使用DNA条形码。研究了胶质母细胞瘤细胞的克隆进化和动力学,并提出了一个模型,其中增殖性异质性是由胶质母细胞瘤干细胞及其后代的同质种群所做出的随机命运决定而得出的。