A novel copper-catalyzed intermolecular carboesterification strategy of alkenes with α-carbonyl alkyl bromides is described. This reaction represents a facile and straightforward access to polysubstituted γ-lactone skeletons, including γ-lactones having ortho-substituted groups on the carbonyl group, in moderate to good yields via a radical strategy, which has good functional group tolerance.

中文翻译：

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铜与α-羰基烷基溴化物和H ₂ O †的铜催化烯烃分子间碳酯化反应自由基介导的γ-内酯合成

描述了一种新型的铜催化烯烃与α-羰基烷基溴化物的分子间碳酯化策略。该反应表示通过自由基策略以中等至良好的产率容易且直接地获得多取代的γ-内酯骨架，包括在羰基上具有邻取代基的γ-内酯，其具有良好的官能团耐受性。