The long-term safety and efficacy of using induced pluripotent stem cell (iPSC)-derived neurons to replace midbrain dopaminergic neurons lost in Parkinson disease (PD) have not been tested in primates. Kikuchi et al. grafted human iPSC-derived midbrain dopaminergic progenitors into the putamen of macaques that

中文翻译：

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神经退行性疾病：走向移植治疗

尚未在灵长类动物中测试使用诱导多能干细胞（iPSC）衍生的神经元替代因帕金森病（PD）丧失的中脑多巴胺能神经元的长期安全性和有效性。菊池等。将人iPSC衍生的中脑多巴胺能祖细胞移植到猕猴的壳中