Cu-Catalyzed tertiary alkylation of α-(trifluoromethyl)styrenes with tertiary alkylmagnesium reagents†,Organic Chemistry Frontiers

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Cu-Catalyzed tertiary alkylation of α-(trifluoromethyl)styrenes with tertiary alkylmagnesium reagents†
Organic Chemistry Frontiers ( IF 5.4 ) Pub Date : 2017-09-18 00:00:00 , DOI: 10.1039/c7qo00716g
Wenpeng Dai _{1,

2,

3,

4,

5} , Yingyin Lin _{1,

2,

3,

4,

5} , Yan Wan _{1,

2,

3,

4,

5} , Song Cao _{1,

2,

3,

4,

5}

Affiliation

A novel and efficient method for the synthesis of 3-tertiary alkylated 1,1-difluorostyrene derivatives via Cu-catalyzed alkylation of α-(trifluoromethyl)styrenes with tertiary alkylmagnesium reagents at room temperature was developed.

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