The intracellular delivery of nanomaterials and drugs has been attracting increasing research interest, mainly because of their important effects and functions in several organelles. Targeting specific organelles can help treat or decrease the symptoms of diabetes, cancer, infectious, and autoimmune diseases. Tuning biological and chemical properties enables the creation of functionalized nanomaterials with enhanced intracellular uptake, ability to escape premature lysosome degradation, and to reach a specific target. Here, we provide an update of recent advances in the intracellular delivery mechanisms that could help drugs reach their target more efficiently.

中文翻译：

---

增强纳米材料细胞内递送的策略

纳米材料和药物的细胞内递送吸引了越来越多的研究兴趣，主要是因为它们在多种细胞器中的重要作用和功能。针对特定细胞器可以帮助治疗或减轻糖尿病、癌症、传染病和自身免疫性疾病的症状。调整生物和化学特性可以创建功能化纳米材料，增强细胞内摄取，避免溶酶体过早降解，并达到特定目标。在这里，我们提供了细胞内递送机制的最新进展，可以帮助药物更有效地到达目标。