Enzymes are fundamental biological catalysts responsible for biological regulation and metabolism. The opportunity for enzymes to ‘meet’ nanoparticles and nanomaterials is rapidly increasing due to growing demands for applications in nanomaterial design, environmental monitoring, biochemical engineering, and biomedicine. Therefore, understanding the nature of nanomaterial–enzyme interactions is becoming important. Since 2014, enzymes have been used to modify, degrade, or make nanoparticles/nanomaterials, while numerous nanoparticles/nanomaterials have been used as materials for enzymatic immobilization and biosensors and as enzyme mimicry. Among the various nanoparticles and nanomaterials, metal nanoparticles and carbon nanomaterials have received extensive attention due to their fascinating properties. This review provides an overview about how enzymes meet nanoparticles and nanomaterials.

酶是负责生物调节和代谢的基本生物催化剂。由于对纳米材料设计，环境监测，生化工程和生物医学应用的需求不断增长，酶“满足”纳米颗粒和纳米材料的机会正在迅速增加。因此，了解纳米材料与酶相互作用的本质变得很重要。自2014年以来，酶已被用于修饰，降解或制造纳米颗粒/纳米材料，而许多纳米颗粒/纳米材料已被用作酶固定化和生物传感器的材料以及酶的模仿。在各种纳米颗粒和纳米材料中，金属纳米颗粒和碳纳米材料由于其引人入胜的性能而受到广泛关注。