Analyses of the genetic architecture of complex diseases such as coronary artery disease (CAD) have revealed that most genetic variants are located in non-coding regions of the genome. As regulatory variants can act over long genomic distances, the causal gene and specific mechanism through which

中文翻译：

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遗传学：从非编码风险变异到CAD的生物学机制

对诸如冠状动脉疾病（CAD）等复杂疾病的遗传结构的分析表明，大多数遗传变异体位于基因组的非编码区域。由于调节性变体可以在较长的基因组距离上起作用，因此可以通过因果基因和特定机制