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A Self-Killing Rabies Virus That Leaves a Trace on the DNA
Trends in Neurosciences ( IF 15.9 ) Pub Date : 2017-10-01 , DOI: 10.1016/j.tins.2017.08.005
William Menegas , Naoshige Uchida , Mitsuko Watabe-Uchida

Although modified rabies viruses have emerged as a powerful tool for tracing the inputs to genetically defined populations of neurons, the toxicity of the virus has limited its utility. A recent study employed a self-inactivating rabies (SiR) virus that enables recording or manipulation of targeted neurons for months.

中文翻译:

一种在 DNA 上留下痕迹的自杀狂犬病病毒

尽管经过修饰的狂犬病病毒已成为追踪基因定义的神经元群体的输入的强大工具,但病毒的毒性限制了其效用。最近的一项研究采用了一种自灭活狂犬病 (SiR) 病毒,它可以记录或操纵目标神经元数月。
更新日期:2017-10-01
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