The glycoprotein (GP) of ebolaviruses participates in a critical membrane fusion process to establish infection of a cell and therefore, represents an important target of both vaccines and antivirals. The latest reports on pan-ebolavirus monoclonal antibodies in small animal models may offer promising outcomes and insight into how best to target the GP in vaccine and antiviral discovery.

中文翻译：

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中和威胁：泛埃博拉病毒抗体闭合循环

埃博拉病毒的糖蛋白（GP）参与关键的膜融合过程以建立细胞感染，因此代表了疫苗和抗病毒药的重要目标。关于小动物模型中的全埃博拉病毒单克隆抗体的最新报告可能会提供令人鼓舞的结果，并有助于深入了解如何在疫苗和抗病毒发现中最有效地靶向GP。