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Uncovering Gene Regulatory Networks Controlling Plant Cell Differentiation
Trends in Genetics ( IF 13.6 ) Pub Date : 2017-06-21 , DOI: 10.1016/j.tig.2017.05.002
Colleen Drapek 1 , Erin E Sparks 1 , Philip N Benfey 2
Affiliation  

The development of multicellular organisms relies on the precise regulation of cellular differentiation. As such, there has been significant effort invested to understand the process through which an immature cell undergoes differentiation. In this review, we highlight key discoveries and advances that have contributed to our understanding of the transcriptional networks underlying Arabidopsis root endodermal differentiation. To conclude, we propose perspectives on how advances in molecular biology, microscopy, and nucleotide sequencing will provide the tools to test the biological significance of these gene regulatory networks (GRN).



中文翻译:


揭示控制植物细胞分化的基因调控网络



多细胞生物的发育依赖于细胞分化的精确调控。因此,人们投入了大量精力来了解未成熟细胞分化的过程。在这篇综述中,我们重点介绍了有助于我们理解拟南芥根内胚层分化的转录网络的关键发现和进展。最后,我们提出了关于分子生物学、显微镜学和核苷酸测序的进步如何提供工具来测试这些基因调控网络(GRN)的生物学意义的观点。

更新日期:2017-06-21
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