当前位置: X-MOL 学术Trends Genet. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
On the Origin of lncRNAs: Missing Link Found
Trends in Genetics ( IF 13.6 ) Pub Date : 2017-08-01 , DOI: 10.1016/j.tig.2017.07.005
Joaquín M. Espinosa

Non-coding (nc)RNAs known as enhancer-derived RNAs (eRNAs) and as long ncRNAs (lncRNAs) have received much attention, but their true functional specialization and evolutionary origins remain obscure. The recent characterization of Bloodlinc, an eRNA derived from a super-enhancer that also functions as a lncRNA, suggests that lncRNAs can evolve from eRNAs.



中文翻译:

关于lncRNA的起源:发现缺失的链接

非编码(nc)RNA被称为增强子来源的RNA(eRNA)和长的ncRNA(lncRNA),受到了广泛的关注,但是它们的真正功能专一性和进化起源仍然晦涩难懂。Bloodlinc是一种来自超级增强子的eRNA,它也起着lncRNA的作用,最近的表征表明lncRNA可以从eRNA进化而来。

更新日期:2017-08-01
down
wechat
bug