Different influenza A viruses (IAVs) infect the same cell in a host, and can subsequently produce new viruses through genome reassortment. By combining padlock probe RNA labeling with a single-cell analysis, a new approach effectively captures IAV genome trafficking and defines a time window for genome reassortment from same-cell coinfections.

中文翻译：

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IAV基因组在单细胞水平上的可视化

不同的甲型流感病毒（IAV）感染宿主中的同一细胞，随后可以通过基因组重排产生新病毒。通过将挂锁探针RNA标记与单细胞分析相结合，一种新方法可有效捕获IAV基因组运输，并为从同细胞合并感染中进行基因组重排确定时间窗。