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Optimization and Interpretation of Serial QuantiFERON Testing to Measure Acquisition of Mycobacterium tuberculosis Infection
American Journal of Respiratory and Critical Care Medicine ( IF 19.3 ) Pub Date : 2017-09-01 , DOI: 10.1164/rccm.201704-0817ocpubmed:28737960 , , Hennie Geldenhuys, Nicole Bilek, Simbarashe Mabwe, Deborah Abrahams, Lebohang Makhethe, Mzwandile Erasmus, Alana Keyser, Asma Toefy, Yolundi Cloete, Frances Ratangee, Thomas Blauenfeldt, Morten Ruhwald, Gerhard Walzl, Bronwyn Smith, Andre G. Loxton, Willem A. Hanekom, Jason R. Andrews, Maria D. Lempicki, Ruth Ellis, Ann M. Ginsberg, Mark Hatherill
American Journal of Respiratory and Critical Care Medicine ( IF 19.3 ) Pub Date : 2017-09-01 , DOI: 10.1164/rccm.201704-0817ocpubmed:28737960 , , Hennie Geldenhuys, Nicole Bilek, Simbarashe Mabwe, Deborah Abrahams, Lebohang Makhethe, Mzwandile Erasmus, Alana Keyser, Asma Toefy, Yolundi Cloete, Frances Ratangee, Thomas Blauenfeldt, Morten Ruhwald, Gerhard Walzl, Bronwyn Smith, Andre G. Loxton, Willem A. Hanekom, Jason R. Andrews, Maria D. Lempicki, Ruth Ellis, Ann M. Ginsberg, Mark Hatherill
Rationale: Conversion from a negative to positive QuantiFERON-TB test is indicative of Mycobacterium tuberculosis (Mtb) infection, which predisposes individuals to tuberculosis disease. Interpretation of serial tests is confounded by immunological and technical variability.
中文翻译：
用于量测结核分枝杆菌感染的串行QuantiFERON测试的优化和解释
基本原理： QuantiFERON-TB测试从阴性转为阳性表明结核分枝杆菌（Mtb）感染，这使个体容易患上结核病。串行测试的解释与免疫学和技术的可变性相混淆。
更新日期：2017-09-05
中文翻译：
用于量测结核分枝杆菌感染的串行QuantiFERON测试的优化和解释
基本原理： QuantiFERON-TB测试从阴性转为阳性表明结核分枝杆菌（Mtb）感染，这使个体容易患上结核病。串行测试的解释与免疫学和技术的可变性相混淆。
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