The effectiveness of noninvasive treatment for neurological disease is generally limited by the poor entry of therapeutic agents into the central nervous system (CNS). Most CNS drugs cannot permeate into the brain parenchyma because of the blood-brain barrier thus, overcoming this problem has become one of the most significant challenges in the development of neurological therapeutics. Nanotechnology has emerged as an innovative alternative for treating neurological diseases. In fact, rapid advances in nanotechnology have provided promising solutions to this challenge. This review highlights the applications of nanomaterials in the developing neurological field and discusses the evidence for their efficacies.

神经系统疾病的非侵入性治疗的有效性通常受到治疗剂进入中枢神经系统（CNS）的不良影响的限制。由于血脑屏障，大多数中枢神经系统药物不能渗透到脑实质中，因此，克服这一问题已成为神经治疗学发展中最重大的挑战之一。纳米技术已经成为治疗神经系统疾病的创新选择。实际上，纳米技术的飞速发展已经为应对这一挑战提供了有希望的解决方案。这篇综述突出了纳米材料在发展中的神经学领域的应用，并讨论了其功效的证据。