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Aspergillus section Nidulantes (formerly Emericella): Polyphasic taxonomy, chemistry and biology
Studies in Mycology ( IF 14.1 ) Pub Date : 2016-10-19 , DOI: 10.1016/j.simyco.2016.10.001
A.J. Chen , J.C. Frisvad , B.D. Sun , J. Varga , S. Kocsubé , J. Dijksterhuis , D.H. Kim , S.-B. Hong , J. Houbraken , R.A. Samson

Aspergillus section Nidulantes includes species with striking morphological characters, such as biseriate conidiophores with brown-pigmented stipes, and if present, the production of ascomata embedded in masses of Hülle cells with often reddish brown ascospores. The majority of species in this section have a sexual state, which were named Emericella in the dual name nomenclature system. In the present study, strains belonging to subgenus Nidulantes were subjected to multilocus molecular phylogenetic analyses using internal transcribed spacer region (ITS), partial β-tubulin (BenA), calmodulin (CaM) and RNA polymerase II second largest subunit (RPB2) sequences. Nine sections are accepted in subgenus Nidulantes including the new section Cavernicolus. A polyphasic approach using morphological characters, extrolites, physiological characters and phylogeny was applied to investigate the taxonomy of section Nidulantes. Based on this approach, section Nidulantes is subdivided in seven clades and 65 species, and 10 species are described here as new. Morphological characters including colour, shape, size, and ornamentation of ascospores, shape and size of conidia and vesicles, growth temperatures are important for identifying species. Many species of section Nidulantes produce the carcinogenic mycotoxin sterigmatocystin. The most important mycotoxins in Aspergillus section Nidulantes are aflatoxins, sterigmatocystin, emestrin, fumitremorgins, asteltoxins, and paxillin while other extrolites are useful drugs or drug lead candidates such as echinocandins, mulundocandins, calbistrins, varitriols, variecolins and terrain. Aflatoxin B1 is produced by four species: A. astellatus, A. miraensis, A. olivicola, and A. venezuelensis.



中文翻译:

曲霉Nidulantes(以前称为Emericella):多相分类学,化学和生物学

Nidulantes的曲霉部分包括具有明显形态特征的物种,例如带有棕色色素柄的biseriate分生孢子,以及如果存在的话,被包埋在Hülle细胞团块中且通常带有红棕色的孢子孢子的子囊。此部分中的大多数物种都具有性状态,在双重名称命名系统中被命名为Emericella。在本研究中,使用内部转录间隔区(ITS),部分β-微管蛋白(BenA),钙调蛋白(CaM)和RNA聚合酶II第二大亚基(RPB2)对属于Nidulantes属的菌株进行了多基因座分子系统发育分析。)序列。Nidulantes属中接受9个部分,包括新的Cavernicolus部分运用形态学特征,外泌体,生理学特征和系统发育的多相方法研究了Nidulantes切片的分类学。基于这种方法,将Nidulantes部分细分为7个进化枝和65种,这里将10种描述为新的。形态特征包括子囊孢子的颜色,形状,大小和装饰,分生孢子和囊泡的形状和大小,生长温度对于鉴定物种很重要。Nidulantes切片的许多种产生致癌性霉菌毒素sterigmatocystin。最重要的霉菌毒素Nidulantes的曲霉菌部分是黄曲霉毒素,sterostertocystin,emestrin,fumitremorgins,astelltoxins和paxillin,而其他外泌体则是有用的药物或候选药物,例如棘孢菌素,mulundocandins,calbistrins,varitriols,variecolins和地形。黄曲霉毒素B 1由四种物种产生:astellatus,A。miiraensis,A。olivicolaA.委内瑞拉。

更新日期:2016-10-19
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