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Genetic insights into mammalian heart regeneration.
Nature Genetics ( IF 31.7 ) Pub Date : 2017-Aug-30 , DOI: 10.1038/ng.3942
Ana Vujic , Vinícius Bassaneze , Richard T Lee

Genetic and functional analyses of 120 mouse strains have identified a heart regeneration candidate gene that modulates the contractile sarcomeric apparatus. This gene, Tnni3k, controls the frequency of the mononuclear, diploid cardiomyocyte population, which affects cardiomyocyte proliferative potential after injury.

中文翻译:

哺乳动物心脏再生的遗传见解。

对120个小鼠品系的遗传和功能分析已确定了可调节收缩型肌节装置的心脏再生候选基因。Tnni3k这个基因控制着单核二倍体心肌细胞的频率,这会影响受伤后心肌细胞的增殖潜能。
更新日期:2017-08-31
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