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In the Hunger Games, the Winner Takes Everything
Trends in Biochemical Sciences ( IF 11.6 ) Pub Date : 2017-08-28 , DOI: 10.1016/j.tibs.2017.08.004 Franziska Püschel , Cristina Muñoz-Pinedo
中文翻译:
在饥饿游戏中,胜利者应有尽有
更新日期:2017-08-28
Trends in Biochemical Sciences ( IF 11.6 ) Pub Date : 2017-08-28 , DOI: 10.1016/j.tibs.2017.08.004 Franziska Püschel , Cristina Muñoz-Pinedo
Entosis is an atypical form of cell death that occurs when a cell engulfs and kills another cell. A recent article by Overholtzer and colleagues indicates that glucose deprivation promotes entosis. AMP-activated protein kinase (AMPK) activation in the loser cells triggers their engulfment and elimination by winner cells, which endure starvation.
中文翻译:
在饥饿游戏中,胜利者应有尽有
Entosis是细胞死亡的一种非典型形式,当细胞吞噬并杀死另一个细胞时就会发生。Overholtzer及其同事最近发表的一篇文章指出,葡萄糖缺乏会促进肠胃炎。失败者细胞中的AMP激活的蛋白激酶(AMPK)激活触发其吞噬和消除,而存活者则忍受饥饿。