With a few exceptions, cancers typically carry more than one driver mutation, sometimes five, ten, or more, and these driver mutations do not necessarily assort randomly. In this issue of Cancer Cell, Mina et al. systematically characterize patterns of co-mutation and mutual exclusivity in 6,456 cancers across 23 tumor types.

中文翻译：

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癌症基因的派系和分裂。

除少数例外，癌症通常携带一个以上的驱动突变，有时为五个，十个或更多，并且这些驱动突变不一定随机分类。在本期《癌细胞》中，Mina等人。系统地表征了23种肿瘤类型中的6,456种癌症的共突变和互斥模式。