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Human toxocariasis.
The Lancet ( IF 168.9 ) Pub Date : 2018-01-01 , DOI: 10.1016/s1473-3099(17)30331-6
Guangxu Ma,Celia V Holland,Tao Wang,Andreas Hofmann,Chia-Kwung Fan,Rick M Maizels,Peter J Hotez,Robin B Gasser

Parasitic nematodes of the genus Toxocara are socioeconomically important zoonotic pathogens. These parasites are usually directly transmitted to the human host via the faecal-oral route and can cause toxocariasis and associated complications, including allergic and neurological disorders. Although tens of millions of people are estimated to be exposed to or infected with Toxocara spp, global epidemiological information on the relationship between seropositivity and toxocariasis is limited. Recent findings suggest that the effect of toxocariasis on human health is increasing in some countries. Here we review the salient background on Toxocara and biology, summarise key aspects of the pathogenesis, diagnosis, and treatment of toxocariasis, describe what is known about its geographic distribution and prevalence, and make some recommendations for future research towards the prevention and control of this important disease.

中文翻译:

人类弓蛔虫病。

弓蛔虫属寄生线虫是社会经济上重要的人畜共患病原体。这些寄生虫通常通过粪口途径直接传播到人类宿主,并可引起弓蛔虫病和相关并发症,包括过敏和神经系统疾病。尽管估计有数千万人接触或感染弓蛔虫属,但有关血清阳性与弓蛔虫病之间关系的全球流行病学信息有限。最近的研究结果表明,在一些国家,弓蛔虫病对人类健康的影响正在增加。在这里,我们回顾了弓蛔虫病和生物学的显着背景,总结了弓蛔虫病的发病机制、诊断和治疗的关键方面,描述了对其地理分布和患病率的了解,并为未来预防和控制该病的研究提出了一些建议。重要的疾病。
更新日期:2017-12-21
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