Photocatalytically active nanoparticles (PCNPs) are extensively investigated for numerous environmental and energy related applications. Independent from their photocatlytic properties, many PCNPs are established as additives for industrial materials (e.g. paintings or coatings) or even in foods, textiles and cosmetics, which leads to high production amounts. Furthermore, researchers are constantly developing new materials in order to optimize the photocatalytic efficiency and optical properties. The increasing material diversity and production amounts are accompanied by growing concerns regarding potential (eco-) toxicological hazards. This paper outlines current knowledge of nanoparticle-cell interaction and critically surveys corresponding in vitro and in vivo assays. It particularly reviews experimental work addressing photoinduced effects on cells and organisms. The work also gives a brief overview on the medical applications of PCNPs.

光催化活性纳米颗粒（PCNPs）已被广泛研究用于许多与环境和能源有关的应用。与其光催化性能无关，许多PCNP被确立为工业材料（例如油漆或涂料）甚至食品，纺织品和化妆品中的添加剂，这导致了高产量。此外，研究人员正在不断开发新材料，以优化光催化效率和光学性能。材料多样性和产量的增加伴随着对潜在（生态）毒理学危害的日益关注。本文概述相应纳米颗粒-细胞相互作用的现有知识和危重调查在体外和体内分析。它特别回顾了解决光诱导对细胞和生物体影响的实验工作。该工作还简要概述了PCNP的医学应用。