This review article highlights the research focused on the synthesis of polylactide (PLA) based copolymers by combination of reversible-deactivation radical polymerization (RDRP) techniques with ring-opening polymerization (ROP) processes. In particular atom-transfer radical polymerization (ATRP), reversible addition-fragmentation chain transfer (RAFT) polymerization, and nitroxide-mediated polymerization (NMP) will be addressed as RDRP techniques mechanistically different from ROP in the design of various sophisticated macromolecular structures. The combination of ROP with RDRP techniques has been extensively applied to prepare PLA copolymers. We discuss the synthetic methods applicable to prepare linear and star-shaped block copolymers by use of heterofunctional initiators as well as other end functionalization methods. This is complemented with the adaption of the synthetic pathways generally used for the preparation of comb and graft copolymers, i.e., macromonomer, grafting-from and grafting-onto approaches, to the requirements of PLA-based building blocks.

这篇综述文章重点介绍了将可逆失活自由基聚合（RDRP）技术与开环聚合（ROP）工艺相结合，以合成基于聚丙交酯（PLA）的共聚物为重点的研究。特别是原子转移自由基聚合（ATRP），可逆加成-断裂链转移（RAFT）聚合和氮氧化物介导的聚合（NMP）将作为RDRP技术在各种复杂的大分子结构设计上与ROP机理不同的技术来解决。ROP与RDRP技术的结合已广泛应用于制备PLA共聚物。我们讨论了适用于通过使用杂官能引发剂以及其他末端官能化方法制备线性和星形嵌段共聚物的合成方法。即大分子单体，从接枝和接枝的方法，以达到基于PLA的构建基块的要求。