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New Functionalities for Paper-Based Sensors Lead to Simplified User Operation, Lower Limits of Detection, and New Applications
Annual Review of Analytical Chemistry ( IF 5.9 ) Pub Date : 2016-06-15 00:00:00 , DOI: 10.1146/annurev-anchem-071015-041605 Josephine C. Cunningham 1 , Paul R. DeGregory 1 , Richard M. Crooks 1
更新日期：2016-06-15
Annual Review of Analytical Chemistry ( IF 5.9 ) Pub Date : 2016-06-15 00:00:00 , DOI: 10.1146/annurev-anchem-071015-041605 Josephine C. Cunningham 1 , Paul R. DeGregory 1 , Richard M. Crooks 1
Affiliation
In the last decade, paper analytical devices (PADs) have evolved into sophisticated yet simple sensors with biological and environmental applications in the developed and developing world. The focus of this review is the technological improvements that have over the past five years increased the applicability of PADs to real-world problems. Specifically, this review reports on advances in sample processing, fluid flow control, signal amplification, and component integration. Throughout, we have sought to emphasize advances that retain the main virtues of PADs: low cost, portability, and simplicity.
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