High-throughput sequencing technologies have revolutionized how we think about viruses. Investigators can now go beyond pathogenic viruses and have access to the thousands of viruses that inhabit our bodies without causing clinical symptoms. By studying their interactions with each other, with other microbes, and with host genetics and immune systems, we can learn how they affect health and disease. This article reviews current knowledge of the composition and diversity of the human virome in physiologically healthy individuals. It focuses on recent results from metagenomics studies and discusses the contribution of bacteriophages and eukaryotic viruses to human health.

中文翻译：

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无症状个体的元基因组学和人类病毒。

高通量测序技术彻底改变了我们对病毒的看法。研究人员现在可以超越致病性病毒，并且可以在不引起临床症状的情况下接触居住在我们体内的数千种病毒。通过研究它们彼此之间，与其他微生物之间以及与宿主遗传学和免疫系统之间的相互作用，我们可以了解它们如何影响健康和疾病。本文回顾了生理健康个体中人类病毒的组成和多样性的最新知识。它着重于宏基因组学研究的最新结果，并讨论了噬菌体和真核病毒对人类健康的贡献。