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Peptide-Based and Polypeptide-Based Gene Delivery Systems
Topics in Current Chemistry ( IF 8.6 ) Pub Date : 2017-03-09 , DOI: 10.1007/s41061-017-0115-x
Jie Chen , Xiuwen Guan , Yingying Hu , Huayu Tian , Xuesi Chen

Peptide-based and polypeptide-based gene carriers are emerging as the most potentially useful agents in the field of gene therapy. Here we summarize the methods used for the preparation of peptides and polypeptides, address the primary types of peptide-based gene delivery systems, demonstrate their applications in gene therapy, and attempt to propose possible future directions in the development of peptide-based and polypeptide-based gene carriers for specific applications.



中文翻译:

基于肽和基于多肽的基因递送系统

基于肽和基于多肽的基因载体正在成为基因治疗领域中最潜在有用的药物。在这里,我们总结了用于制备肽和多肽的方法,介绍了基于肽的基因递送系统的主要类型,展示了它们在基因治疗中的应用,并尝试为基于肽和多肽的开发提出可能的未来方向特定应用的基于基因的载体。

更新日期:2017-03-09
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