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Recombinant ADAMTS13 for Immune Thrombotic Thrombocytopenic Purpura
The New England Journal of Medicine ( IF 158.5 ) Pub Date : 2024-05-09 , DOI: 10.1056/nejmoa2402567 Pavan K. Bendapudi 1 , Brody H. Foy 1 , Sarah B. Mueller 1 , Jun Liu 1 , Louis M. Feingold 1 , Kristen E. Burke 1 , Wendy Cruz 1 , Maria Y. Chen 1 , Emily S. Lau 1 , Rachel L. Goldberg 1 , Ishan Tatake 1 , Shelby C. Wilkinson 1 , Brian J. Carney 1 , James R. Stone 1 , Doyun Park 1 , Alzira R. Avelino 1 , Sajjad Hassan 1 , Chester Andrzejewski 1 , Kristen N. Ruby 1 , Kenneth D. Friedman 1 , Patricia A.R. Brunker 1 , Rebecca K. Leaf 1 , John Higgins 1 , Walter H. Dzik 1 , Jonathan A. Stefely 1 , Robert S. Makar 1
The New England Journal of Medicine ( IF 158.5 ) Pub Date : 2024-05-09 , DOI: 10.1056/nejmoa2402567 Pavan K. Bendapudi 1 , Brody H. Foy 1 , Sarah B. Mueller 1 , Jun Liu 1 , Louis M. Feingold 1 , Kristen E. Burke 1 , Wendy Cruz 1 , Maria Y. Chen 1 , Emily S. Lau 1 , Rachel L. Goldberg 1 , Ishan Tatake 1 , Shelby C. Wilkinson 1 , Brian J. Carney 1 , James R. Stone 1 , Doyun Park 1 , Alzira R. Avelino 1 , Sajjad Hassan 1 , Chester Andrzejewski 1 , Kristen N. Ruby 1 , Kenneth D. Friedman 1 , Patricia A.R. Brunker 1 , Rebecca K. Leaf 1 , John Higgins 1 , Walter H. Dzik 1 , Jonathan A. Stefely 1 , Robert S. Makar 1
Affiliation
In patients with immune thrombotic thrombocytopenic purpura (iTTP), autoantibodies against the metalloprotease ADAMTS13 lead to catastrophic microvascular thrombosis. However, the potential benefit...
中文翻译：
重组 ADAMTS13 治疗免疫性血栓性血小板减少性紫癜
在免疫性血栓性血小板减少性紫癜 (iTTP) 患者中，针对金属蛋白酶 ADAMTS13 的自身抗体会导致灾难性的微血管血栓形成。然而，潜在的好处...
更新日期：2024-05-09
中文翻译：
重组 ADAMTS13 治疗免疫性血栓性血小板减少性紫癜
在免疫性血栓性血小板减少性紫癜 (iTTP) 患者中，针对金属蛋白酶 ADAMTS13 的自身抗体会导致灾难性的微血管血栓形成。然而，潜在的好处...
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