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The resistance patterns and molecular characteristics of ESBL/AmpC-producing Escherichia coli from captive panda ecosystem in China
Ecotoxicology and Environmental Safety ( IF 6.8 ) Pub Date : 2024-05-09 , DOI: 10.1016/j.ecoenv.2024.116395 Gang Shu , Ting gan , Ziqin Lin , Ying Liu , Jingyi Chen , Chengdong Wang , Linhua Deng , Caiwu Li , Li-Jen Chang , Wei Zhang , Haohuan Li , Funeng Xu , Hualing Fu , Juchun Lin
Ecotoxicology and Environmental Safety ( IF 6.8 ) Pub Date : 2024-05-09 , DOI: 10.1016/j.ecoenv.2024.116395 Gang Shu , Ting gan , Ziqin Lin , Ying Liu , Jingyi Chen , Chengdong Wang , Linhua Deng , Caiwu Li , Li-Jen Chang , Wei Zhang , Haohuan Li , Funeng Xu , Hualing Fu , Juchun Lin
() plays an important ecological role, and is a useful bioindicator to recognize the evolution of resistance in human, animal and environment. Recently, extended-spectrum β-lactamases (ESBL) producing has posed a threat to public health. Generally, captive healthy giant pandas are not exposed to antibiotics; however, they still acquire antimicrobial resistant bacteria. In order to understand whether there is an exchange of resistance genes within the ecosystems of captive giant pandas, this study explored resistance characteristics of 330 commensal isolates from feces of giant pandas, the surroundings, and breeders. Isolates from different sources showed similar resistance phenotype, and ESBL/AmpC-producing isolates showed more profound resistance to antibiotics than non-ESBL/AmpC-producing isolates (<0.05).
更新日期：2024-05-09
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