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Self-sacrificing-induced defect enhances the oxidase-like activity of MnOOH for total antioxidant capacity evaluation
Analytica Chimica Acta ( IF 6.2 ) Pub Date : 2024-04-29 , DOI: 10.1016/j.aca.2024.342664
Peng Hu , Zihao Zuo , Xiang wen Ma , Chengzhou Zhu , Liuyong Hu , Wenling Gu

Nanozymes is a kind of nanomaterials with enzyme catalytic properties. Compared with natural enzymes, nanozymes merge the advantages of both nanomaterials and natural enzymes, which is highly important in applications such as biosensing, clinical diagnosis, and food inspection. In this study, we prepared β-MnOOH hexagonal nanoflakes with a high oxygen vacancy ratio by utilizing SeO as a sacrificial agent. The defect-rich MnOOH hexagonal nanoflakes demonstrated excellent oxidase-like activity, catalyzing the oxidation substrate in the presence of O, thereby rapidly triggering a color reaction. Consequently, a colorimetric sensing platform was constructed to assess the total antioxidant capacity in commercial beverages. The strategy of introducing defects in situ holds great significance for the synthesis of a series of high-performance metal oxide nanozymes, driving the development of faster and more efficient biosensing and analysis methods.

中文翻译:


自我牺牲诱导的缺陷增强了 MnOOH 的类氧化酶活性,用于总抗氧化能力评估



纳米酶是一类具有酶催化特性的纳米材料。与天然酶相比,纳米酶融合了纳米材料和天然酶的优点,在生物传感、临床诊断、食品检验等应用中具有重要意义。在这项研究中,我们利用SeO作为牺牲剂制备了具有高氧空位比的β-MnOOH六方纳米片。富含缺陷的MnOOH六角纳米片表现出优异的类氧化酶活性,在O存在的情况下催化氧化底物,从而快速引发颜色反应。因此,构建了比色传感平台来评估商业饮料中的总抗氧化能力。原位引入缺陷的策略对于合成一系列高性能金属氧化物纳米酶具有重要意义,推动更快、更高效的生物传感和分析方法的发展。
更新日期:2024-04-29
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