Neurological soft signs (NSS) are subtle motor control impairments that include involuntary movements and abnormalities of motor coordination, sensory integration and lateralization. They engage different brain networks, including the prefrontal networks that support the higher cognitive functions that are dysfunctional in obsessive-compulsive disorder (OCD). This study investigated the relationships between the presence of NSS and patients' severity of OCD symptoms, insight, and treatment resistance in a sample of 63 patients. Treatment-resistance was assessed considering all the treatments the patients received during the course of their disease. The four dimensions of OCD defined in the dimensional obsessive-compulsive scale were considered. Links between the patients’ cognitive abilities and NSS were assessed using tests targeting specifically the core components of executive functions.

中文翻译：

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神经软体征作为强迫症患者子集的特征标记，这些患者具有低洞察力和认知能力改变

神经软体征 (NSS) 是微妙的运动控制障碍，包括不自主运动以及运动协调、感觉统合和偏侧化的异常。它们涉及不同的大脑网络，包括支持在强迫症（OCD）中功能失调的高级认知功能的前额叶网络。这项研究以 63 名患者为样本，调查了 NSS 的存在与患者强迫症症状的严重程度、自知力和治疗抵抗之间的关系。考虑患者在病程期间接受的所有治疗来评估治疗抵抗力。考虑了维度强迫量表中定义的强迫症的四个维度。使用专门针对执行功能核心组成部分的测试来评估患者认知能力和 NSS 之间的联系。