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Multiple E3 ligases act as antiviral factors against SARS-CoV-2 via inducing the ubiquitination and degradation of ORF9b
Journal of Virology ( IF 5.4 ) Pub Date : 2024-05-06 , DOI: 10.1128/jvi.01624-23
Miao Yu 1, 2 , Jie Li 2 , Wenying Gao 1, 3 , Zhaolong Li 1, 3 , Wenyan Zhang 1, 3
Affiliation  

Ubiquitination is an important post-translational modification that regulates multiple biological processes, including viral replication. Identification of E3 ubiquitin ligases that target viral proteins for degradation can provide novel targets for ...

中文翻译:

多种E3连接酶通过诱导ORF9b泛素化和降解作为抗SARS-CoV-2的抗病毒因子

泛素化是一种重要的翻译后修饰,可调节多种生物过程,包括病毒复制。鉴定以病毒蛋白为目标进行降解的 E3 泛素连接酶可以为……提供新的靶标。
更新日期:2024-05-07
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