Zirconium terephthalate UiO-66 has aroused great interest in catalysis since it exhibits significant flexibility and compatibility for accommodating a high number of defects as well as exceptional thermal and chemical stability. Until now, many works have focused on the modulations of the Zr₆-oxo clusters in UiO-66 in terms of diverse synthesis, advanced characterizations, and their catalytic applications. To achieve high catalytic efficiency, it is still highly desired for rationally constructing and modulating the Zr₆-oxo clusters with exposed catalytic sites and diverse microenvironments for advanced catalysis. In this review, we provide a comprehensive summary of recent progress on the synthesis of defective UiO-66, qualitative and quantitative characterizations, as well as a logical overview of heterogeneous catalytic applications over the past few years. Finally, the outlooks for the research paradigm of defective UiO-66 are discussed.

对苯二甲酸锆 UiO-66 引起了催化领域的极大兴趣，因为它表现出显着的灵活性和相容性，可容纳大量缺陷以及出色的热稳定性和化学稳定性。到目前为止，许多工作都集中在 UiO-66 中 Zr ₆ -oxo 团簇的多样化合成、高级表征及其催化应用方面的调节。为了实现高催化效率，仍然非常需要合理构建和调节具有暴露催化位点和多样化微环境的Zr ₆ -氧簇以进行先进催化。在这篇综述中，我们全面总结了缺陷 UiO-66 合成的最新进展、定性和定量表征，以及过去几年多相催化应用的逻辑概述。最后对缺陷UiO-66的研究范式进行了展望。