Rapid and quantitative detection of isoquercitrin (Isq) has been attracting much attention due to its outstanding pharmacological and physiological activities. Herein, an interesting 48-metal Zn(II)-Nd(III) nanocluster (, molecular sizes 1.3 × 2.8 × 3.1 nm) with salen-type Schiff base ligand was constructed as molecular sensor for the luminescence detection of Isq. exhibits visible ligand-centered emission and NIR luminescence of Nd(III), and shows ratiometric fluorescence response to Isq with high sensitivity even in the presence of other interferences. The fluorescence sensing behavior can be expressed by a second-order equation / = *[Isq] + *[Isq] + , which is used to quantitatively analyze the Isq concentrations in DMF and FCS. The LODs to Isq for the ligand-centered and lanthanide emissions of in DMF are 0.21 μM and 0.11 nM, respectively. The quenching of the ligand-centered emission of caused by Isq is attributed to the competitive absorption of light energy and “inner effect”, while, the luminescence enhancement is due to the “antenna effect”.

中文翻译：

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基于高核 Zn(II)-Nd(III) 纳米分子传感器快速可靠地检测异槲皮苷

异槲皮苷（Isq）的快速定量检测因其突出的药理和生理活性而备受关注。在此，构建了一种具有萨伦型席夫碱配体的有趣的48金属Zn(II)-Nd(III)纳米团簇（分子尺寸1.3×2.8×3.1 nm）作为用于Isq发光检测的分子传感器。表现出可见的 Nd(III) 配体中心发射和近红外发光，即使在存在其他干扰的情况下，也能以高灵敏度显示对 Isq 的比率荧光响应。荧光传感行为可以用二阶方程 / = *[Isq] + *[Isq] + 表示，用于定量分析 DMF 和 FCS 中的 Isq 浓度。 DMF 中配体中心发射和镧系元素发射的 Isq 的 LOD 分别为 0.21 μM 和 0.11 nM。 Isq引起的配体中心发射的猝灭归因于光能的竞争吸收和“内效应”，而发光增强则归因于“天线效应”。