A mild condition to synthesize active anticancer agents based on oleate epoxide derivatives from palm oil was successfully performed. A new perspective on the bioactivity of oleate epoxides has been revealed. Oleate epoxides exhibited potent and selective activity against WiDr, T47D, and HeLa cancer cells. Moreover, the molecular docking results suggest that oleate epoxides inhibit the FASN protein receptor.

中文翻译：

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棕榈油衍生的油酸酯环氧化物作为新型抗癌剂：合成、细胞毒性评估和针对 FASN 蛋白的分子对接研究

成功地在温和的条件下合成了基于棕榈油油酸酯环氧化物衍生物的活性抗癌剂。揭示了油酸酯环氧化物生物活性的新视角。油酸酯环氧化物对 WiDr、T47D 和 HeLa 癌细胞表现出有效的选择性活性。此外，分子对接结果表明油酸酯环氧化物会抑制FASN蛋白受体。