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Synthesis of ɑ‐aryl‐oxindoles via Grignard reaction with isatin in the presence of diphenyl phosphite
Chemistry - An Asian Journal ( IF 4.1 ) Pub Date : 2024-05-03 , DOI: 10.1002/asia.202400297
Xinxin Zhang 1 , Pengkai Wang 2 , Songlin Zhang 3
Affiliation  

A protocol has been developed for the synthesis of α‑aryl‐oxindoles from isatin and Grignard reagents in the presence of diphenyl phosphite for the first time. This reaction was conveniently carried out under mild conditions in a one‐pot fashion with moderate to excellent yields.

中文翻译:

亚磷酸二苯酯存在下,靛红通过格氏反应合成 ɑ-芳基-羟吲哚

首次开发了在亚磷酸二苯酯存在下由靛红和格氏试剂合成 α-芳基-羟吲哚的方案。该反应在温和条件下以一锅方式方便地进行,具有中等至优异的产率。
更新日期:2024-05-03
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