Synthesis of heteroaryl ortho‐substituted anilines is hitherto challenging. Herein we report scope and limitation of method for annulation of 1‐(2‐nitroaryl)pyrroles and derivatives of 2‐aminobenzyl alcohol to afford ortho‐substituted pyrrolo[1,2‐a]quinoxalin‐4‐yl anilines. Reaction conditions contained elemental sulfur as promoter, while were tolerant of a wide range of aryl and heteroaryl amines. Our method would offer a feasible tactic to yield anilines steric bulk with ortho heterocyclic substituents.

中文翻译：

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元素硫促进合成邻位吡咯并[1,2-a]喹喔啉-4-基苯胺的通用方法

杂芳基的合成正射‐取代苯胺迄今为止仍具有挑战性。在此，我们报告了 1-(2-硝基芳基)吡咯和 2-氨基苯甲醇衍生物环化方法的范围和限制，以提供正射‐取代的吡咯并[1,2‐A]喹喔啉-4-基苯胺。反应条件包含元素硫作为促进剂，同时能够耐受多种芳基和杂芳基胺。我们的方法将提供一种可行的策略来产生苯胺空间体积正射杂环取代基。