Episodic memory retrieval is associated with the holistic neocortical reinstatement of all event information, an effect driven by hippocampal pattern completion. However, whether holistic reinstatement occurs, and whether hippocampal pattern completion continues to drive reinstatement, after a period of consolidation is unclear. Theories of systems consolidation predict either a time-variant or time-invariant role of the hippocampus in the holistic retrieval of episodic events. Here, we assessed whether episodic events continue to be reinstated holistically and whether hippocampal pattern completion continues to facilitate holistic reinstatement following a period of consolidation. Female and male human participants learned "events" that comprised multiple overlapping pairs of event elements (e.g., person–location, object–location, location–person). Importantly, encoding occurred either immediately before or 24 h before retrieval. Using fMRI during the retrieval of events, we show evidence for holistic reinstatement, as well as a correlation between reinstatement and hippocampal pattern completion, regardless of whether retrieval occurred immediately or 24 h after encoding. Thus, hippocampal pattern completion continues to contribute to holistic reinstatement after a delay. However, our results also revealed that some holistic reinstatement can occur without evidence for a corresponding signature of hippocampal pattern completion after a delay (but not immediately after encoding). We therefore show that hippocampal pattern completion, in addition to a nonhippocampal process, has a role in holistic reinstatement following a period of consolidation. Our results point to a consolidation process where the hippocampus and neocortex may work in an additive, rather than compensatory, manner to support episodic memory retrieval.

情景记忆检索与所有事件信息的整体新皮质恢复有关，这是由海马模式完成驱动的效应。然而，经过一段时间的巩固后，是否会发生整体恢复，以及海马模式的完成是否继续推动恢复尚不清楚。系统整合理论预测海马在情景事件的整体检索中发挥时变或时不变的作用。在这里，我们评估了情景事件是否继续整体恢复，以及海马模式完成是否继续促进巩固期后的整体恢复。女性和男性参与者学习的“事件”包含多个重叠的事件元素对（例如，人-位置、物体-位置、位置-人）。重要的是，编码发生在检索之前或检索前 24 小时。在事件检索过程中使用功能磁共振成像，我们显示了整体恢复的证据，以及恢复和海马模式完成之间的相关性，无论检索是立即发生还是编码后 24 小时发生。因此，海马模式的完成在延迟后继续有助于整体恢复。然而，我们的结果还表明，在没有证据表明延迟后（但不是在编码后立即）海马模式完成的相应特征的情况下，可能会发生一些整体恢复。因此，我们表明，除了非海马过程之外，海马模式完成在巩固期后的整体恢复中也发挥着作用。我们的结果指出了一个巩固过程，其中海马体和新皮质可能以附加而非补偿的方式工作来支持情景记忆检索。