Burns are a global public health problem, which brings great challenges to public health and the economy. Severe burns often lead to systemic infection, shock, multiple organ failure, and even death. With the increasing demand for the therapeutic effect of burn wounds, traditional dressings have been unable to meet people's needs due to their single function and many side effects. In this context, electrospinning shows a great prospect on the way to open up advanced wound dressings that promote wound repairing and prevent infection. With its large specific surface area, high porosity, and similar to natural extracellular matrix (ECM), electrospun nanofibers can load drugs and accelerate wound healing. It provides a promising solution for the treatment and management of burn wounds. This review article introduces the concept of burn and the types of electrospun nanofibers, then summarizes the polymers used in electrospun nanofiber dressings. Finally, the drugs (plant extracts, small molecule drugs and nanoparticles) loaded with electrospun burn dressings are summarized. Some promising aspects for developing commercial electrospun burn dressings are proposed.

中文翻译：

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静电纺纳米纤维作为燃烧敷料的最新进展

烧伤是一个全球性的公共卫生问题，给公共卫生和经济带来巨大挑战。严重烧伤常导致全身感染、休克、多器官衰竭，甚至死亡。随着人们对烧伤创面治疗效果的要求越来越高，传统敷料由于功能单一、副作用较多，已无法满足人们的需求。在此背景下，静电纺丝在开辟促进伤口修复、预防感染的先进伤口敷料之路上展现出了巨大的前景。电纺纳米纤维具有比表面积大、孔隙率高、与天然细胞外基质（ECM）相似的特点，可以负载药物并加速伤口愈合。它为烧伤创面的治疗和管理提供了一种有前途的解决方案。本文介绍了烧伤的概念和静电纺纳米纤维的类型，然后总结了静电纺纳米纤维敷料中使用的聚合物。最后对电纺烧伤敷料负载的药物（植物提取物、小分子药物和纳米颗粒）进行了总结。提出了开发商业化电纺烧伤敷料的一些有前景的方面。