Bioaerosols produced during animal production have potential adverse effects on the health of workers and animals. Our objective was to investigate characteristics, antibiotic-resistance genes (ARGs), and health risks of bioaerosols in various animal barns. Poultry and swine barns had high concentrations of airborne bacteria (11156 and 10917 CFU/m, respectively). , , , , , , and were dominant pathogenic bacteria in animal barns, with Firmicutes being the most abundant bacterial phylum. Based on linear discriminant analysis effect size (LEfSe), there were more discriminative biomarkers in cattle barns than in poultry or swine barns, although the latter had the highest abundance of bacterial pathogens and high abundances of ARGs (including M, O, Q, W 1, 2, A, B) and 1). Based on network analyses, there were higher co-occurrence patterns between bacteria and ARGs in bioaerosol from swine barns. Furthermore, in these barns, relative abundance of bacteria in bioaerosol samples was greatly affected by environmental factors, mainly temperature, relative humidity, and concentrations of CO, NH, and PM. This study provided novel data regarding airborne bio-contaminants in animal enclosures and an impetus to improve management to reduce potential health impacts on humans and animals.

中文翻译：

---

动物谷仓中生物气溶胶的特征和健康影响：一项综合研究

动物生产过程中产生的生物气溶胶对工人和动物的健康具有潜在的不利影响。我们的目标是调查各种动物谷仓中生物气溶胶的特征、抗生素抗性基因 (ARG) 和健康风险。家禽和猪舍的空气细菌浓度很高（分别为 11156 和 10917 CFU/m）。 、 、 、 、 、 和 是畜舍中的优势致病菌，其中厚壁菌门是最丰富的细菌门。基于线性判别分析效应大小 (LEfSe)，牛舍中的判别性生物标志物比家禽或猪舍中的要多，尽管后者的细菌病原体丰度最高，并且 ARG 丰度较高（包括 M、O、Q、W）。 1、2、A、B) 和 1)。根据网络分析，猪舍生物气溶胶中的细菌和 ARG 之间存在较高的共现模式。此外，在这些谷仓中，生物气溶胶样品中细菌的相对丰度很大程度上受到环境因素的影响，主要是温度、相对湿度以及CO、NH和PM的浓度。这项研究提供了有关动物围栏中空气传播的生物污染物的新数据，并推动改进管理以减少对人类和动物的潜在健康影响。