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The Tricuspid Valve: A Review of Pathology, Imaging, and Current Treatment Options: A Scientific Statement From the American Heart Association
Circulation ( IF 37.8 ) Pub Date : 2024-04-25 , DOI: 10.1161/cir.0000000000001232
Laura J. Davidson , Gilbert H.L. Tang , Edwin C. Ho , Marat Fudim , Tiberio Frisoli , Anton Camaj , Margaret T. Bowers , Sofia Carolina Masri , Pavan Atluri , Joanna Chikwe , Peter J. Mason , Jason C. Kovacic , George D. Dangas ,

Tricuspid valve disease is an often underrecognized clinical problem that is associated with significant morbidity and mortality. Unfortunately, patients will often present late in their disease course with severe right-sided heart failure, pulmonary hypertension, and life-limiting symptoms that have few durable treatment options. Traditionally, the only treatment for tricuspid valve disease has been medical therapy or surgery; however, there have been increasing interest and success with the use of transcatheter tricuspid valve therapies over the past several years to treat patients with previously limited therapeutic options. The tricuspid valve is complex anatomically, lying adjacent to important anatomic structures such as the right coronary artery and the atrioventricular node, and is the passageway for permanent pacemaker leads into the right ventricle. In addition, the mechanism of tricuspid pathology varies widely between patients, which can be due to primary, secondary, or a combination of causes, meaning that it is not possible for 1 type of device to be suitable for treatment of all cases of tricuspid valve disease. To best visualize the pathology, several modalities of advanced cardiac imaging are often required, including transthoracic echocardiography, transesophageal echocardiography, cardiac computed tomography, and cardiac magnetic resonance imaging, to best visualize the pathology. This detailed imaging provides important information for choosing the ideal transcatheter treatment options for patients with tricuspid valve disease, taking into account the need for the lifetime management of the patient. This review highlights the important background, anatomic considerations, therapeutic options, and future directions with regard to treatment of tricuspid valve disease.

中文翻译:

三尖瓣:病理学、影像学和当前治疗方案的回顾:美国心脏协会的科学声明

三尖瓣疾病是一个经常被忽视的临床问题,与显着的发病率和死亡率相关。不幸的是,患者常常在病程晚期出现严重的右心衰竭、肺动脉高压和生命限制症状,而这些症状几乎没有持久的治疗选择。传统上,三尖瓣疾病的唯一治疗方法是药物治疗或手术。然而,在过去几年中,人们对使用经导管三尖瓣疗法来治疗以前治疗选择有限的患者越来越感兴趣,并取得了成功。三尖瓣解剖结构复杂,毗邻重要的解剖结构,如右冠状动脉和房室结,是永久起搏器引线进入右心室的通道。此外,三尖瓣病变的机制因患者而异,可能是原发性、继发性或多种原因的组合,这意味着一种类型的装置不可能适合治疗所有三尖瓣病例疾病。为了最好地观察病理情况,通常需要多种先进心脏成像技术,包括经胸超声心动图、经食管超声心动图、心脏计算机断层扫描和心脏磁共振成像,以最好地观察病理情况。这种详细的成像为三尖瓣疾病患者选择理想的经导管治疗方案提供了重要信息,同时考虑到患者终生管理的需要。这篇综述强调了三尖瓣疾病治疗的重要背景、解剖学考虑、治疗选择和未来方向。
更新日期:2024-04-27
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