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A novel dual near-infrared fluorescent probe for bioimaging and visualization of viscosity in acute alcoholic liver injury
Chemical Communications ( IF 4.9 ) Pub Date : 2024-04-24 , DOI: 10.1039/d4cc01222d
Ruonan Wang 1 , Xucong Zhou 1 , Bingxue Li 1 , Ru Ding 1 , Jingqian Han 1 , Ying Wang 2, 3 , Aixia Meng 1 , Jin Zhou 1
Affiliation  

A dual NIR fluorescent probe Cy-ND is developed for viscosity sensing with λex/em = 766/806 nm, making it apt for biological analysis, whose response is validated through DFT and TDDFT computations. Cy-ND successfully detected viscosity changes amidst acute alcohol-induced liver injury and liver ischemia-reperfusion injury.

中文翻译:

一种新型双近红外荧光探针,用于急性酒精性肝损伤的生物成像和粘度可视化

双 NIR 荧光探针Cy-ND专为粘度传感而开发,λ ex/em = 766/806 nm,使其适用于生物分析,其响应通过 DFT 和 TDDFT 计算进行验证。Cy-ND成功检测了急性酒精性肝损伤和肝脏缺血再灌注损伤中的粘度变化。
更新日期:2024-04-24
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