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RNA-based therapies targeting APOC3 lower triglyceride levels in patients with hypertriglyceridaemia
Nature Reviews Cardiology ( IF 49.6 ) Pub Date : 2024-04-23 , DOI: 10.1038/s41569-024-01034-w
Karina Huynh

Three randomized clinical trials presented at ACC.24 demonstrate that olezarsen and plozasiran, RNA-based therapies that target APOC3, can robustly reduce plasma triglyceride levels in patients with moderate to severe hypertriglyceridaemia.

中文翻译:

基于 RNA 的靶向 APOC3 疗法可降低高甘油三酯血症患者的甘油三酯水平

ACC.24 上提出的三项随机临床试验表明,olezarsen 和 plozasiran 是靶向 APOC3 的基于 RNA 的疗法,可以显着降低中度至重度高甘油三酯血症患者的血浆甘油三酯水平。
更新日期:2024-04-24
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