In this work, the perovskite fluorescent nanocrystals (CsPbBr) were successfully synthesized and wrapped with SiO shell, utilized for the assembly of solid-state detection strip capable of conveniently and specifically detection of aflatoxin B (AFB). The SiO coating aimed to enhance the stability of CsPbBr nanocrystals. The resulting CsPbBr@SiO material exhibited remarkable fluorescence properties, and further self-assembled onto solid-state plate, generating AFB-specific quenched fluorescence at a specific wavelength of 515 nm. When combined with the capture of AFB by magnetic nanoparticles conjugated with aptamers (MNPs-Apt), it was achieved the good separation and specific detection of AFB toxin in food matrices. The constructed fluorescent solid-state detection strip based on CsPbBr@SiO exhibited good response to AFB toxin within a linear range of 0.1–100 ng mL and an impressive detection limit as low as 0.053 ng mL. This presents a new strategy for the rapid screening and convenient detection of highly toxic AFB.

中文翻译：

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基于SiO2壳稳定钙钛矿纳米晶的荧光固态试纸条应用于磁性适体检测食品中黄曲霉毒素B1毒素

本工作成功合成了钙钛矿荧光纳米晶（CsPbBr），并用SiO2壳包裹，用于组装固态检测条，能够方便、特异地检测黄曲霉毒素B（AFB）。 SiO涂层旨在增强CsPbBr纳米晶体的稳定性。所得CsPbBr@SiO材料表现出显着的荧光特性，并进一步自组装到固态板上，在515 nm特定波长下产生AFB特异性猝灭荧光。结合核酸适配体磁性纳米颗粒（MNPs-Apt）对AFB的捕获，实现了食品基质中AFB毒素的良好分离和特异性检测。基于CsPbBr@SiO构建的荧光固态检测条在0.1-100 ng mL的线性范围内对AFB毒素表现出良好的响应，并且检测限低至0.053 ng mL。这为快速筛查和便捷检测剧毒AFB提供了新策略。