In the wake of escalating medicine prices worldwide, Veronika Wirtz and colleagues argue for refocusing the WHO Model List of Essential Medicines on the needs of low and middle income countries, while retaining its global relevance as a model process ### Key messages First published in 1977, the World Health Organization (WHO) Model List of Essential Medicines has been one of the most effective and recognised tools to promote equitable access to medicines, prioritising those that satisfy the health priorities of the population.12 Essential medicines are “selected with due regard of public health relevance, evidence on efficacy and safety, and comparative cost-effectiveness.”3 The list is updated every two years; Tedros Adhanom Ghebreyesus, director general of WHO, announced publication of the 23rd Model List of Essential Medicines in July 2023. This version sets a new record for the number of medicines included (502).4 The children’s list, which now includes 361 medicines, was first published in 2007 to consider children’s medicines needs more systematically and has since been published every two years alongside the main model list.45 The inclusion of many high priced medicines over the past decade has prompted debate about the focus …

中文翻译：

---

重新调整世界卫生组织基本药物标准清单以满足低收入和中等收入国家的需求

随着全球药品价格不断上涨，Veronika Wirtz 及其同事主张重新将世卫组织基本药物标准清单的重点放在低收入和中等收入国家的需求上，同时保留其作为标准流程的全球相关性 ### 关键信息 首次发表于1977 年，世界卫生组织 (WHO) 基本药物标准清单一直是促进公平获得药物的最有效和公认的工具之一，优先考虑那些满足人口健康优先事项的药物。 12 基本药物是“根据适当的标准选择的”。考虑到公共卫生相关性、功效和安全性证据以及相对成本效益。”3 该清单每两年更新一次；世卫组织总干事谭德塞宣布于 2023 年 7 月发布第 23 版基本药物标准目录。该版本收录药品数量创下新纪录（502 种）。4 儿童目录目前包括 361 种药品，于 2007 年首次发布，旨在更系统地考虑儿童药品需求，此后每两年与主要模型清单一起发布一次。 45 过去十年中纳入了许多高价药品，引发了关于重点的争论……