Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington’s disease,Proceedings of the National Academy of Sciences of the United States of America

当前位置： X-MOL 学术 › Proc. Natl. Acad. Sci. U.S.A. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington’s disease
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2024-04-12 , DOI: 10.1073/pnas.2322924121
Kyung-Hee Kim _{1,

2} , Eun Pyo Hong _{1,

2} , Yukyeong Lee _{1,

2} , Zachariah L. McLean _{1,

2,

3} , Emanuela Elezi ₁ , Ramee Lee ₄ , Seung Kwak ₄ , Branduff McAllister _{1,

5} , Thomas H. Massey ₅ , Sergey Lobanov ₅ , Peter Holmans ₅ , Michael Orth ₆ , Marc Ciosi ₇ , Darren G. Monckton ₇ , Jeffrey D. Long _{8,

9} , Diane Lucente ₁ , Vanessa C. Wheeler _{1,

2} , Marcy E. MacDonald _{1,

2,

3} , James F. Gusella _{1,

3,

10} , Jong-Min Lee _{1,

2,

3}

Affiliation

Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114
Department of Neurology, Harvard Medical School, Boston, MA 02115
Medical and Population Genetics Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142
CHDI Foundation, Princeton, NJ 08540
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, United Kingdom
University Hospital of Old Age Psychiatry and Psychotherapy, Bern University, CH-3000 Bern 60, Switzerland
School of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom
Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242
Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA 52242
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115