Examining the relationship between the responses of a number of different cognitive trainings on cognitive functioning in middle-aged and elderly patients with mild cognitive impairment. Randomized controlled experimental studies published publicly from the time of inception to October 30, 2023 were searched through Web of Science, PubMed, Embase, and Cochrane library databases. Traditional and network meta-analyses were performed using Stata 17.0 software. Fifty papers on 4 types of cognitive training were included. Traditional meta-analysis showed that virtual reality training ( = 0.53, 95%: [0.36,0.70], = 0.00), neuropsychological training ( = 0.44, 95%: [0.18,0.70], = 0.00), cognitive strategy training ( = 0.26, 95%: [0.16,0.36], = 0.00), and cognitive behavioral therapy ( = 0.25, 95%: [0.08,0.41], = 0.00) all had significant improvement effects on the cognitive function of middle-aged and elderly patients with mild cognitive impairment. Network meta-analysis revealed neuropsychological training as the best cognitive training, and subgroup analysis of cognitive function subdimensions showed that neuropsychological training had the best effects on working memory, lobal cognitive function, memory, and cognitive flexibility improvement. Meanwhile, virtual reality training had the best effects on processing speed, verbal ability, overall executive function, spatial cognitive ability, and attention improvement. Cognitive training can significantly improve the cognitive function of middle-aged and elderly patients with mild cognitive impairment, and neuropsychological training is the best intervention, most effective in interventions lasting more than 8 weeks.

中文翻译：

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不同认知训练对轻度认知障碍患者认知功能影响的网络荟萃分析

研究多种不同认知训练对轻度认知障碍中老年患者认知功能的反应之间的关系。通过 Web of Science、PubMed、Embase 和 Cochrane 图书馆数据库检索了从开始到 2023 年 10 月 30 日公开发表的随机对照实验研究。使用 Stata 17.0 软件进行传统和网络荟萃分析。包括 50 篇关于 4 种认知训练的论文。传统荟萃分析显示，虚拟现实训练（= 0.53，95％：[0.36，0.70]，= 0.00），神经心理训练（= 0.44，95％：[0.18，0.70]，= 0.00），认知策略训练（= 0.26、95%:[0.16,0.36],=0.00)、认知行为治疗(=0.25,95%:[0.08,0.41],=0.00)均对中老年人认知功能有显着改善作用患有轻度认知障碍的患者。网络荟萃分析显示神经心理训练是最好的认知训练，认知功能子维度的亚组分析显示神经心理训练对工作记忆、脑叶认知功能、记忆力和认知灵活性的改善效果最好。同时，虚拟现实训练对处理速度、言语能力、整体执行功能、空间认知能力和注意力改善效果最好。认知训练可以显着改善中老年轻度认知障碍患者的认知功能，而神经心理训练是最好的干预措施，持续8周以上的干预措施最有效。