When transcription by RNA polymerase II is stalled by ultraviolet-induced DNA damage, it recruits repair factors, leading to excision of the damaged site and DNA synthesis to fill the gap. Three new studies show that, for aldehyde-induced DNA crosslinks, repair is activated by the same factors, but without base excision and gap filling.

中文翻译：

---

添加转录偶联修复途径

当 RNA 聚合酶 II 的转录因紫外线诱导的 DNA 损伤而停滞时，它会招募修复因子，导致受损位点的切除和 DNA 合成以填补空白。三项新研究表明，对于醛诱导的 DNA 交联，修复是由相同的因素激活的，但没有碱基切除和间隙填充。